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Symbol
Name
ID
Zc3h12a
zinc finger CCCH type containing 12A
MGI:2385891
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
enlarged spleen
abnormal class switch recombination
increased plasma cell number
increased memory T cell number
increased leukocyte cell number
increased IgA level
increased IgG1 level
increased IgG2a level
increased IgG2b level
increased IgG3 level
increased IgG level
increased IgM level
increased immunoglobulin level
abnormal circulating chemokine level
increased circulating tumor necrosis factor level
enlarged lymph nodes
abnormal chemokine secretion
increased interferon-gamma secretion
increased interleukin-1 beta secretion
increased interleukin-12b secretion
increased interleukin-6 secretion
increased tumor necrosis factor secretion
increased autoantibody level
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
abnormal acute inflammation
granulomatous inflammation
increased inflammatory response
bile duct inflammation
liver inflammation
Availability Mouse Genotype
Zc3h12atm1Aki/Zc3h12atm1Aki
Zc3h12atm1Fum/Zc3h12atm1Fum
Zc3h12atm1c(EUCOMM)Hmgu/Zc3h12atm1c(EUCOMM)Hmgu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Zc3h12atm1c(EUCOMM)Hmgu/Zc3h12atm1c(EUCOMM)Hmgu
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory